In a pre-clinical study, the NTU Singapore team fed insulin-containing nanoparticles to rats and found that insulin increased in their blood minutes later.
Insulin therapy is often an important part of treatment for diabetes, a metabolic disease that affects 422 million people globally . In Singapore, the number of diabetics is expected to grow to 1 million – almost a fifth of the population – in 2050 .
Delivering insulin orally would be preferable over insulin jabs for patients because it causes less pain than jabs, and could thus lead to improved patient compliance. But oral dosage remains a challenge. As insulin is a protein, it gets broken down in the gastrointestinal tract before it can even reach the bloodstream to regulate blood glucose.
Read full article at NTU Singapore
Photo credit: NTU Singapore